Parathyroid hormone family

Identifiers

Symbol

Parathyroid

Pfam

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe
PDBsum	structure summary

Parathyroid hormone (PTH) is a polypeptidic hormone that elevates calcium level by dissolving the salts in bone and preventing their renal excretion. The 'parathyroid hormone-related protein' (PTH-rP) is structurally related to PTH^[1] and seems to play a physiological role in lactation, possibly as a hormone for the mobilization and/or transfer of calcium to the milk. PTH and PTH-rP bind to the same G-protein coupled receptor.

Subfamilies

Parathyroid hormone subtype IPR003625
Parathyroid hormone-related protein IPR003626

Human proteins containing this domain

PTH; PTHLH;

References

^ Martin TJ, Allan EH, Caple IW, Care AD, Danks JA, Diefenbach-Jagger H, Ebeling PR, Hammonds G, Heath JA, Gillespie MT (1989). "Parathyroid hormone-related protein: isolation, molecular cloning, and mechanism of action". Recent Prog. Horm. Res. 45: 467–502. PMID 2682846.

This article incorporates text from the public domain Pfam and InterPro IPR001415